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艾美捷科技特约代理Axon Medchem产品


Axon Medchem的业务之一,是独有的Axon Ligands配体库,在世界范围内,被认为是药物研发的标准。这其中,针对850余种生物靶标(包括细胞信号、基因转录、凋亡、细胞周期调控、CNS等),Axon Medchem拥有多达2000余种小分子抑制剂或调节剂。除了配体库,Axon Medchem还是欧洲著名的CRO公司,主要针对生物活性分子和药物类似分子展开合成及协议开发工作,在过去的10年中,Axon Medchem已经发现了多种潜在药物分子,并在生物医药界享有一定的声誉。

 

Axon Medchem is a trusted supplier of high-value life science products, providing Axon Ligands™ as world wide recognized drug reference standards for pharmacological research. With more than 2000 excellent quality small molecule inhibitors or modulators targeting more than 850 biological targets of cell signaling, gene transcription, apoptosis, cell cycle regulation, CNS and many more areas, Axon Medchem aims to facilitate your scientific research and development.  

 

Axon Medchem is also a leading European CRO in medicinal chemistry, specialized in contract research and high-quality synthesis of bio-active and/or drug-like molecules. We have the proven record in developing novel drug candidates and achieving excellence for a decade by providing our dedicated chemistry services for companies and research institutes active in the field of life sciences around the world.

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GORYO Chemical.png

艾美捷科技有限公司,代理GORYO Chemical公司全系列探针产品。


GORYO Chemical公司位于日本札幌市,是一家生产荧光探针的专业化供应商。由于荧光探针的化学特性,使得研究者可以利用它对细胞内运行机理进行可视化研究。GORYO Chemical与东京大学和北海道大学合作,在荧光试剂领域领已取得领先的地位。目前,GORYO Chemical在日本已经开始针对癌症检测推出临床使用的探针,在未来,这将为指导治疗提供新的方法。

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主要产品和服务:

AcidiFluor™ SeriesFluorescent probes to detect acidic pHSize
GC301AcidiFluor™ ORANGE10 μg × 20
GC3011AcidiFluor™ ORANGE10 μg × 10
GC302AcidiFluor™ ORANGE-NHS1 mg
GC303AcidiFluor™ ORANGE-NHS5 μg × 5
GC304AcidiFluor™ ORANGE Labeling Kit5 times labeling
GC305AcidiFluor™ ORANGE-Zymosan A1 mg
GC306AcidiFluor™ ORANGE-Dextran 10k1 mg
GC309AcidiFluor™ ORANGE-Transferrin1 mg
GC310-01HaloTag® AcidiFluor™ ORANGE Ligand30 nmol
GC310-02HaloTag® AcidiFluor™ ORANGE Ligand60 nmol
CalxFluor™ SeriesFluorescent probes to detect calcium ionsSize
GC405CaSiR-1 potassium salt500 µg
GC503CaTM-2 AM500 μg
GC504CaTM-2 AM50 μg × 10
GC5041CaTM-2 AM50 μg × 5
GC507CaTM-3 AM40 nmol × 5
GlycoFluor™ SeriesFluorescent probes to detect glycosidase activitySize
GC601GlycoYELLOW™ –βGal50 μg × 10
GC611GlycoGREEN™-βGal30 nmol × 5
SK4001-01TokyoGreen®–βGal1 mg
SK4002-01TokyoGreen®–βGlu1 mg
SK4003-01TokyoGreen®–βGlcU(Na)1 mg
HaloFluor™ SeriesFluorescent probes combined with Halotag® ligandSize
GC310-01HaloTag® AcidiFluor™ ORANGE Ligand30 nmol
GC310-02HaloTag® AcidiFluor™ ORANGE Ligand60 nmol
A201-01HaloTag® SaraFluor™ 650B ligand15 nmol
A201-02HaloTag ®SaraFluor™ 650B ligand15 nmol × 2
ProteoFluor™ SeriesFluorescent probes to detect protease activity in cancer cellSize
GC801ProteoGREEN™-gGlu20 μg × 10
GC811EP-HMRG30 nmol x 5
StemFluor™ SeriesFluorescent probes to detect human iPS/ES cellsSize
GC7001-01Kyoto Probe 1 (KP-1)10 μg × 5
GC7001-02Kyoto Probe 1 (KP-1)10 μg × 10
SaraFluor™ SeriesFluorescent probes for labeling/imagingSize
ST1003-10SaraFluor™ 488-NHS5 nmol x 5
ST1003-11SaraFluor™ 488-NHS1 mg
ST1003-15SaraFluor™ 488-NHS1 mg x 5
ST1003-21SaraFluor™ 488-maleimide1 mg
ST1003-25SaraFluor™ 488-maleimide1 mg x 5
ST1003-31SaraFluor™ 488-COOH1 mg
ST1003-35SaraFluor™ 488-COOH1 mg x 5
ST1003-41SaraFluor™ 488-NH21 mg
ST1003-45SaraFluor™ 488-NH21 mg x 5
ST1006-10SaraFluor™ 600-NHS5 nmol x 5
ST1006-11SaraFluor™ 600-NHS1 mg
ST1006-15SaraFluor™ 600-NHS1 mg x 5
ST1006-21SaraFluor™ 600-maleimide1 mg
ST1006-25SaraFluor™ 600-maleimide1 mg x 5
ST1006-31SaraFluor™ 600-COOH1 mg
ST1006-35SaraFluor™ 600-COOH1 mg x 5
ST1006-41SaraFluor™ 600-NH21 mg
ST1006-45SaraFluor™ 600-NH21 mg x 5
ST1008-10SaraFluor™ 650-NHS5 nmol x 5
ST1008-11SaraFluor™ 650-NHS1 mg
ST1008-15SaraFluor™ 650-NHS1 mg x 5
ST1008-21SaraFluor™ 650-maleimide1 mg
ST1008-25SaraFluor™ 650-maleimide1 mg x 5
ST1008-31SaraFluor™ 650-COOH1 mg
ST1008-35SaraFluor™ 650-COOH1 mg x 5
ST1008-41SaraFluor™ 650-NH21 mg
ST1008-45SaraFluor™ 650-NH21 mg x 5
ST1010-10SaraFluor™ 700-NHS5 nmol x 5
ST1010-11SaraFluor™ 700-NHS1 mg
ST1010-15SaraFluor™ 700-NHS1 mg x 5
ST1010-21SaraFluor™ 700-maleimide1 mg
ST1010-25SaraFluor™ 700-maleimide1 mg x 5
ST1010-31SaraFluor™ 700-COOH1 mg
ST1010-35SaraFluor™ 700-COOH1 mg x 5
ST1010-41SaraFluor™ 700-NH21 mg
ST1010-45SaraFluor™ 700-NH21 mg x 5
ST1011-10SaraFluor™ 720-NHS5 nmol x 5
ST1011-11SaraFluor™ 720-NHS1 mg
ST1011-15SaraFluor™ 720-NHS1 mg x 5
ST1011-21SaraFluor™ 720-maleimide1 mg
ST1011-25SaraFluor™ 720-maleimide1 mg x 5
ST1011-31SaraFluor™ 720-COOH1 mg
ST1011-35SaraFluor™ 720-COOH1 mg x 5
ST1011-41SaraFluor™ 720-NH21 mg
ST1011-45SaraFluor™ 720-NH21 mg x 5
A201-01HaloTag® SaraFluor™ 650B ligand15 nmol
A201-02HaloTag ®SaraFluor™ 650B ligand15 nmol × 2
A202-01SaraFluor™ 650B goat anti-mouse IgG100 μg
A203-01SaraFluor™ 650B goat anti-rat IgG100 μg
A204-01SaraFluor™ 650B goat anti-rabbit IgG100 μg
A208-01SaraFluor™ 650B-NHS100 μg
A209-01SaraFluor™ 650B-maleimide100 μg
A218-01SaraFluor™ 488B-NHS100 μg
MetalloFluor™ SeriesFluorescent probes to detect metall ionSize
GC901FeRhoNox™-150 μg × 10
GC902CopperGREEN™50 nmol × 5
GC903-01FerroFarRed™50 nmol × 5
GC904-01FerroOrange35 nmol × 5
GC904-02FerroOrange35 nmol × 1
SK2001-01ZnAF®-21 mg
SK2002-01ZnAF®-2 DA1 mg
NOFluor™ SeriesFluorescent probes to detect niric oxideSize
SK1001-01DAF-21 mg
SK1002-01DAF-2 DA1 mg
SK1003-01DAF-FM1 mg
SK1004-01DAF-FM DA1 mg
SK1005-01DAR-4M1 mg
SK1006-01DAR-4M AM1 mg
HypoFluor™ SeriesFluorescence probes for hypoxia detectionSize
A101-01MAR25 μg × 5
ROSFluor™ SeriesFluorescent probes to detect reactive oxigen speciesSize
SK3001-02Hydroxyphenyl Fluorescein (HPF)1 mg
SK3002-02Aminophenyl Fluorescein (APF)1 mg
SK3003-01NiSPY-31 mg
GC3004-01OxiORANGE™100 nmol ×5
GC3006-01HySOx20 μg × 5
GC3007-01HYDROP30 nmol × 3
GC3008-01HYDROP-EX30 nmol × 3
FRETFluor™ SeriesFRET based fluorescent probesSize
A401-1QuicGSH3.025 nmol × 5
A401-2QuicGSH3.025 nmol × 2
A402-1SSip-1 DA60 nmol × 3
NIRFluor™ seriesNear infrared fluorescent probes
A501-01ICG-NHS ester1 mg
A501-05ICG-NHS ester1 mg × 5
A501-10ICG-NHS ester1 mg × 10
A502-01ICG-maleimide1 mg
A502-05ICG-maleimide1 mg × 5
A502-10ICG-maleimide1 mg × 10
Bioluminescent seriesFluorescent probes for in vivo imagingSize
RS101-01D-Luciferin potassium salt1 g
POLARIC™ SeriesFluorescent probes for staining cell membrane and bacteriaSize
GC101POLARIC™-500c6F1 μg × 10
GC1011POLARIC™-500c6F1 μg × 5
GC102POLARIC™-500BCS5 μg × 10
GC1021POLARIC™-500BCS5 μg × 5
GC2021POLARIC™-NHS1 mg
GC2031POLARIC™-maleimide1 mg
GC211POLARIC™ Labeling Kit5 times labelng


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艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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Mercodia.png

瑞典MERCODIA公司是免疫诊断产品的开发机构和提供商。MERCODIA长期专注于心血管疾病,糖尿病和肥胖领域的ELISA临床诊断和科研方面的应用,并在全球范围内第一个研发并向市场推出胰岛素(INSULIN)ELISA检测试剂盒和OXLDL ELISA检测试剂盒。MERCODIA与瑞士ROCHE一道成为世界范围内的胰岛素检测的最权威的机构,是WHO推荐的金标准方法和产品,广泛被大学、医院、药厂所使用。

 

MERCODIA的产品理念是为客户提供诊断试剂的最高品质,提供优良的性能和可重复性的方便和易于使用的方法。在产品中使用单克隆抗体的产品,确保长期重复性。

 

Mercodia's Bioanalytical Service provides you with the experience, quality and reliability that are fundamental to a productive partnership. Our experienced team of managers, scientists, technicians and regulatory resources will support you in everything from study design to sample handling. We follow the most recent international guidelines and industry standard white papers for bioanalytical method development and validation.

 

Mercodia AB的主要产品包括:

Mercodia AKURIO Multiplex Islet Hormones

Mercodia Total GLP-1 NL-ELISA

Mercodia Glucagon Control – Low, Medium, High

Mercodia GLP-1 (9-36) amide Control - Low, Medium, High

Mercodia C-peptide ELISA

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艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com


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艾美捷科技代理Gene Tools品牌


Gene Tools是一家生产和销售Morpholino Anti-sense oligos(反义寡核苷酸)的公司,其产品专门用于基因调控的科学研究和药物开发。Gene Tools公司由多位资深科学家组成,为全球客户提供免费的技术咨询和Morpholino 序列设计服务。 Morpholino作为基因调控研究的最佳工具,已被广泛用于:阻断靶mRNA 翻译 (下调基因);诱导RNA选择性剪接 (下调或上调基因);阻断 miRNA;阻断病毒 RNA;阻断 non-coding RNA。


Morpholino介绍

Morpholino属于第三代反义寡核苷酸,主要通过阻断蛋白质翻译过程而达到抑制目标基因功能的作用,目前已经广泛用于发育生物学和细胞学实验中,并取得了非常好的实验效果。

Morpholino以吗啉环类似物为基本骨架,这种独特的结构特性使得Morpholino 具有以下几个特点:

● 与其他类型的反义寡核苷酸相比,Morpholino 能更好地抵抗核酸酶的作用;

● Morpholino 与靶序列结合后通过空间位阻效应发挥作用, 不激活RNaseH,不引起目标基因mRNA 的降解 ;

● 针对翻译起始位点区设计的Morpholino 用于抑制蛋白质的翻译,针对 pre-mRNA 剪切位点区设计的Morpholino 可影响mRNA 剪切,得到不 同的转录本,可以方便地用于目标基因结构域的突变研究;

● 与靶序列结合能力强,可以渗入mRNA 的二级结构, 并且特异性好。

配合Morpholino 的使用,Gene Tools公司开发了相应的递送系统,可以安全、高效地将Morpholino 输送至胞内,因此,Morpholino 也可以用于遗传学研究和新药靶标的发现以及验证。此外,Morpholino 可以标上荧光基团、亲和标签以及活性反应基团,以供不同的研究需要。

Gene Tools代理.png


Gene Tools公司产品介绍

● Custom Morpholino:可以根据目标基因序列定制设计并合成Morpholino,用于体外细胞实验或某些直接显微注射的模型(如斑马鱼、非洲爪蟾胚胎)。

● Vivo-Morpholino:适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。通过特殊的末端修饰,提高了其穿透细胞膜进入组织细胞的能力,使得在成年动物(主要是小鼠、大鼠)中进行系统性基因功能研究成为可能。

● Prepared Control Oligos:根据特定需求合成细胞穿透肽偶联的 Morpholino。适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。


产品名称Short DescriptionOligo sequenceSKU
Standard Control Oligo Negative control oligoCCTCTTACCTCAGTTACAATTTATAPCO-StandardControl-100
Vivo-Morpholino Standard Control OligoNegative Vivo-Morpholino control oligoCCTCTTACCTCAGTTACAATTTATAPCO-VivoStandardControl-100
Random Control Oligo 25-N25-base random sequence mixtureNNNNNNNNNNNNNNNNNNNNNNNNNPCO-RandomControl-25N-100
Zebrafish p53 oligoDanio rerio apoptosis suppression oligoGCGCCATTGCTTTGCAAGAATTGPCO-ZebrafishP53-100
Zebrafish Chordin Positive Control OligoDanio rerio Chordin positive control oligoATCCACAGCAGCCCCTCCATCATCCPCO-ZebrafishChordin-100-F
Clawed Frog Beta Catenin Positive Control OligoXenopus laevis Beta Catenin antisense oligoTTTCAACCGTTTCCAAAGAACCAGGPCO-BetaCatenin-100-F
Green Fluorescent Protein Positive ControlTranslation blocker for GFP targetACAGCTCCTCGCCCTTGCTCACCATPCO-GFPControl-100
Vivo-Morpholino GFP Positive ControlTranslation blocker for GFP target (Vivo-Morpholino)ACAGCTCCTCGCCCTTGCTCACCATPCO-VivoGFPControl-100
Fluoresceinated Vivo-Morpholino Std ControlNegative Vivo-Morpholino control oligo with 5'FluoresceinCCTCTTACCTCAGTTACAATTTATAPCO-FluorVivoStandardControl-100-F


● Endo-Porter:为了解决Morpholino在体外培养细胞中摄取效率低的问题,Gene Tools 开发了 Endo-Porter 这种特殊的转染试剂。它通过温和的内吞体逃逸机制帮助Morpholino进入细胞质。



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Stemmera.jpg

Stemmera公司位于美国加州,主要生产干细胞相关产品,包括检测试剂盒、培养基、抗体、缓冲液,还包括用于干细胞研究的细胞系。

 

Stemmera Inc is a privately owned biotechnology company located in Bay Area, California that focus in developing innovative technology and application solution for stem cell research. Our products include kit, culture medium, reagents, antibodies, buffer and solution, cell lines that are convenient tools used in stem cell research.

 

Stemmera公司主要产品:

(1)Kit

Alkaline Phosphatase (AP) Detection Kit (Ready-to-use)-Blue

Alkaline Phosphatase (AP) Detection Kit (Ready-to-use)-Red

Human Fibroblast (hFIB) Reprogramming Kit

Human Blood Cell (hBLD) Reprogramming Kit

(2)Media

Human ESCs/iPSCs Serum-/ Feeder-Free Medium (hStemSFM)

Human ESCs/iPSCs Xeno-Free Medium (hStemXFM)

Human Fibroblast (hFIB) Reprogramming Medium

Human Blood Cell (hBLD) Reprogramming Medium

Fibroblast Growth Medium

(3)Buffer & Solutions

Non-Enzymatic Cell Dissociation Solution (1X)

Serum-Free Cryopreservation Solution for Human ESCs/iPSCs

0.2% Gelatin

0.1% Gelatin

Universal Cryopreservation Solution

Blood Cell Cryopreservation Solution (1x)

Cell Fixation Solution (4% Paraformaldehyde, PFA)

Cell Fixation Solution (10% Formalin)

Metaphase Arrest Solution (10 μg/ml, 10X)

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艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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Allele Biotechnology.jpg

Allele Biotechnology位于美国圣地亚哥市,主要专注于对生物过程的机制进行探索,以开发生物医学及治疗相关的技术和产品。以各个物种的iPS细胞、人类cGMP iPS细胞及衍生的细胞为材料,Allele Biotechnology利用专利性的非整合细胞编辑方法,开发了出了细胞治疗和药物筛选的技术。Allele Biotechnology具有深厚的基因组修饰和细胞荧光报告因子的经验,为客户提供优异的细胞检测解决方案。Allele Biotechnology还提供荧光蛋白、高效荧光素酶底物、基因分型试剂盒、骆驼抗体等产品;此外还在RNA干扰领域尤其独特的专利。

 

Allele Biotechnology and Pharmaceuticals, Inc. is a private, San Diego-based company that explores the mechanisms of biological processes to develop technologies and products for biomedical research and therapy development.

 

Our mission is to increase accessibility to innovative molecular biology research tools by offering cutting edge technologies in individual products and fully integrated platforms. Allele utilizes proprietary non-integrating cellular reprogramming methods to develop cell therapy and enable drug discovery through the use of human and non-human primate iPS cells, cGMP-grade human iPS cells and their derivatives. With additional expertise in genome modification and unique cell-based fluorescence sensors/reporters, Allele provides advanced cell and assay development solutions. Allele also has developed a wide variety of advanced research tools including superior fluorescent proteins, highly efficient luciferase assay substrates, genotyping kits, and camelid antibodies that have been validated for co-immunoprecipitation, histology, and flow cytometry. The Company has also been a leader in the RNAi field with its patents in Pol III promoter-driven siRNA, shRNA, and miRNA.

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艾美捷科技代理Gelomics品牌全系列产品


Gelomics专注于实现体外人体组织模型的生长,核心在于创新的3D细胞培养解决方案。这种技术模拟了人体组织的真实生长环境,相较于传统的细胞培养方式更为先进和贴近人体实际情况。团队由经验丰富的专业人士组成,他们具备深厚的专业知识和多年的行业经验,致力于推动公司通过3D细胞培养技术实现改变药物发现的愿景,为公司的技术研发和战略发展提供有力支持。所研究的高纯度、可调谐的 GelMA 提供了生物活性和机械控制的最佳平衡,使其成为生物医学研究和再生医学的绝佳选择。甲基丙烯酰明胶 (GelMA) – 冷水鱼皮,具有以下特征:

高度可调:能够精确控制刚度、孔隙率和退化等关键参数。GelMA可以根据不同的研究或应用需求进行定制化调整,满足多样化的实验和生产要求。

● 支持细胞活力和功能:为细胞的附着、增殖和分化提供了符合生物学要求的微环境。这对于细胞的生长和功能表达至关重要,有助于模拟体内真实的细胞生长环境,提高细胞培养的效果和质量。

● 与3D生物打印兼容:既可以单独使用,也能与其他生物材料一起使用,用于创建定制的细胞外基质(ECM),应用于生物制造和组织工程领域。


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▍Gelomics产品列表


分类品名货号
Gelatin Methacryloyl (GelMA)Gelatin Methacryloyl (GelMA) – Bovine BoneSKU0013
Gelatin Methacryloyl (GelMA)Gelatin Methacryloyl (GelMA) – Bovine SkinSKU0024
Gelatin Methacryloyl (GelMA)Gelatin Methacryloyl (GelMA) – Bovine BoneSKU0013
Gelatin Methacryloyl (GelMA)Gelatin Methacryloyl (GelMA) – Porcine SkinSKU0010
LAP - Photoinitiator PowderVisible Light PhotoinitiatorSKU0021
LunaCrosslinker™LunaCrosslinker™ – Visible Light Crosslinking-
LunaGel™ - Cell Recovery KitLunaGel™ - Cell Recovery KitSKU0015
LunaGel™ SystemLunaCrosslinker™ – Visible Light Crosslinking-
LunaGel™ SystemLunaGel™ Ultrapure GelMA – Photocrosslinkable Extracellular MatrixSKU0018
LunaGel™ SystemLunaGel™ Bovine Bone – Photocrosslinkable Extracellular MatrixSKU0009
LunaGel™ SystemLunaGel™ Bovine Skin – Photocrosslinkable Extracellular MatrixSKU0020
LunaGel™ SystemLunaGel™ Cold Water Fish Skin – Photocrosslinkable Extracellular MatrixSKU0011
LunaGel™ SystemLunaGel™ Porcine Skin – Photocrosslinkable Extracellular MatrixSKU0012
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Mediomics公司2001年成立,致力于为学术机构、制药公司、医学研究者、环境研究者提供创新性的检测试剂盒及生物感应物质。Mediomics拥有Patented Bridge-It® Assay Platform、Patented FRET-PINCER® Assay Platform、Patented TRF-PINCER® Assay Platform三大技术平台。

 

Mediomics, LLC provides innovative assay kits and biosensors needed by academic research laboratories, point of care testing, pharmaceutical companies, as well as medical and environmental research markets.  

 

Technology platforms:

(1)Patented Bridge-It® Assay Platform

Bridge-It® Assays are optimized to measure DNA binding proteins, their ligands, and co-regulators. Mediomics’ Bridge-It® assay was based on a simple idea of splitting the DNA binding site for a protein into two DNA half-sites. The presence of the DNA-binding protein or one of its ligands can be detected by FRET (fluorescence resonance energy transfer).

(2)Patented FRET-PINCER® Assay Platform

FRET-PINCER® Assays are a unique system to quantify the concentration of biomarkers, cells, and pathogens in a broad range of biological samples. The patent-protected FRET-PINCER® Assay system detects the concentration of the target molecule by bringing together complementary single-stranded DNAs and their attached fluorophores to produce fluorescent light through FRET (fluorescence resonance energy transfer).

(3)Patented TRF-PINCER® Assay Platform

TRF-PINCER® Assays are a unique system to quantify the concentration of biomarkers, cells, and pathogens in a broad range of biological samples. The patent-protected TRF-PINCER® Assay platform system detects the concentration of the target molecule by bringing together complementary single-stranded DNAs and their attached fluorophores to produce fluorescent light with Time-Resolved Fluorometry (TRF) sensitivity.

 

主要产品线包括:

(1)Bridge-It® Assay

(2)TR-FRET Bridge-It® Assay

(3)FRET-PINCER® Assay

(4)TR-FRET PINCER®Assay

(5)Other

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艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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